Many states add their own money on top of a federal SBIR or STTR award, and some run their own innovation grants for companies based in the state. The rules belong to each state: who qualifies, how much is matched, when the window opens and what the company owes afterward.
Tennessee: Launch Tennessee
| Program | Status | Next deadline | Pre-step | Award | Official page |
|---|---|---|---|---|---|
| SBIR/STTR Matching Fundpre-IPO company headquartered in Tennessee with fewer than 500 employees and a federal notice of award dated July 1, 2025 to September 30, 2026 | Closed, next cycle | FY27 application window ran October 5 to October 16, 2026 | Federal SBIR/STTR notice of award | Up to 50% of the federal award: Phase I up to $100,000, Phase II up to $300,000 | Official page |
New York: Empire State Development (NYSTAR)
| Program | Status | Next deadline | Pre-step | Award | Official page |
|---|---|---|---|---|---|
| Innovation Matching Grants ProgramNew York small business with 100 or fewer employees applying for or awarded an SBIR or STTR within 12 months | Closed, next cycle | Round 6 closed; rounds open at 9 AM on the second Wednesday of October and April | Federal SBIR/STTR application or award | Up to 50% of the federal award: Phase I up to $100,000, Phase II up to $200,000 | Official page |
Colorado: Office of Economic Development and International Trade
| Program | Status | Next deadline | Pre-step | Award | Official page |
|---|---|---|---|---|---|
| Advanced Industries Early-Stage Capital and Retention Grantcompany headquartered in Colorado or with at least 50% of employees in Colorado, under $20 million raised and under $10 million in annual revenue | Opens soon | Application opens January 4, 2027; windows run January to March and July to September | Company to state cash match of 2 to 1 | Up to $250,000 per project, in some cases up to $500,000 | Official page |
Massachusetts: Massachusetts Clean Energy Center
| Program | Status | Next deadline | Pre-step | Award | Official page |
|---|---|---|---|---|---|
| CatalystMassachusetts based early stage climatetech company with four or fewer full time equivalent employees and under $2.5 million raised or in revenue over five years | Closed, next cycle | Fall 2026 round closed September 30, 2026; the spring 2027 round opens in winter 2027 | Application on masscec.com | Grants of up to $75,000 | Official page |
| InnovateMassMassachusetts based climatetech company with a demonstration partner, TRL 5 to 8; at least 20% cash cost share | Closed, next cycle | RFP application deadline was October 20, 2026 | Demonstration partner and cash cost share | Up to $350,000 | Official page |
| AmplifyMasscost share and adders for federal prime awards such as ARPA-E, DOE and NSF; SBA small business with a significant Massachusetts presence | Closed, next cycle | Closed for fiscal year 2027 | Federal prime award | Up to $300,000 | Official page |
California: California Institute for Regenerative Medicine
| Program | Status | Next deadline | Pre-step | Award | Official page |
|---|---|---|---|---|---|
| CLIN2 clinical trial awardCalifornia or non-California for-profit or nonprofit organizations; for-profit co-funding of 30% for first in human trials and 50% for Phase 2 and later | Closed, next cycle | Applications closed October 30, 2026, 2 PM PT; next CLIN2 deadline not yet posted | Consultation with CIRM before the deadline | $8 million to $15 million | Official page |
| PDEV preclinical development awardCalifornia organization with more than 50% of W-2 staff in California, for-profit or nonprofit | Closed, next cycle | Application and consultation period closed October 8, 2026 | Consultation with CIRM | Up to $13 million per award | Official page |
North Carolina: Department of Commerce
| Program | Status | Next deadline | Pre-step | Award | Official page |
|---|---|---|---|---|---|
| One North Carolina Small Business Programmatching grants for federal SBIR and STTR awards and incentive grants; eligibility in the program guidelines | Open | Applications accepted until June 30, 2027, or until funds are exhausted | Federal SBIR/STTR award or application per the guidelines | FY2027: $1,920,000 for matching grants and $210,000 for incentive grants | Official page |
Nebraska: Department of Economic Development
| Program | Status | Next deadline | Pre-step | Award | Official page |
|---|---|---|---|---|---|
| Nebraska SBIR/STTR Grant ProgramPhase 0 proposal support plus Phase I and Phase II matches for Nebraska businesses | Open | Open July 7, 2026 to June 30, 2027, 11:55 PM CT, or until funds are exhausted | Federal SBIR/STTR application or award | Phase 0 up to $5,000; Phase I up to $150,000 or 65% of the federal grant; Phase II up to $300,000 or 65% | Official page |
Alabama: Innovate Alabama
| Program | Status | Next deadline | Pre-step | Award | Official page |
|---|---|---|---|---|---|
| Supplemental Grant Programmatch for federal SBIR and STTR awards to Alabama companies | Closed, next cycle | Applications are currently closed | Federal SBIR/STTR award | 50% of the federal award: Phase I up to $100,000, Phase II up to $250,000 | Official page |
Montana: Department of Commerce
| Program | Status | Next deadline | Pre-step | Award | Official page |
|---|---|---|---|---|---|
| Montana SBIR/STTR Matching Funds ProgramMontana companies with a federal SBIR or STTR award | Open, rolling | Applications can be submitted at any time | Federal SBIR/STTR award | Up to $30,000 per phase, available yearly | Official page |
Indiana: Indiana Economic Development Corporation
| Program | Status | Next deadline | Pre-step | Award | Official page |
|---|---|---|---|---|---|
| SBIR/STTR matchcompany headquartered in Indiana with a federal SBIR or STTR award | Open, rolling | No application window stated; rolling | Federal SBIR/STTR award | $0.50 per federal dollar: up to $50,000 Phase I, up to $75,000 Phase II, $150,000 lifetime | Official page |
Hawaii: Hawaii Technology Development Corporation
| Program | Status | Next deadline | Pre-step | Award | Official page |
|---|---|---|---|---|---|
| HSBIR FY27 Phase I matchcompany registered and compliant in Hawaii, work performed in Hawaii, with an active federal SBIR/STTR award within the past 12 months | Open | Applications accepted October 23, 2026 to December 11, 2026, 11:59 PM | Federal SBIR/STTR award | Up to 50% match of the Phase I award, up to $75,000 | Official page |
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